Hs04721259_cn

• Gene Symbol: LOC101927854
• Assay Reference Genome Location: Chr.3:24172203 on build GRCh38
• Cytoband: 3p24.2

Target Gene Details

• Entrez Gene ID: 101927854
• Gene Name: uncharacterized LOC101927854
• Gene Aliases: -
• Location: Chr.3:24151324-24189956 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC101927854	NR_121667.1
	CB994391.1

Target Gene Details

• Entrez Gene ID: 7068
• Gene Name: thyroid hormone receptor beta
• Gene Aliases: C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
• Location: Chr.3:24117153-24495281 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
THRB	NM_000461.4			NP_000452.2
	NM_001128176.2			NP_001121648.1
	NM_001128177.1			NP_001121649.1
	NM_001252634.1			NP_001239563.1
	XM_005265421.4			XP_005265478.1
	XM_005265423.4			XP_005265480.1
	XM_005265424.3			XP_005265481.1
	XM_006713317.3			XP_006713380.1
	XM_006713318.3			XP_006713381.1
	XM_011534046.2			XP_011532348.1
	XM_011534047.2			XP_011532349.1
	XM_011534048.2			XP_011532350.1
	XM_011534049.2			XP_011532351.1
	XM_011534050.2			XP_011532352.1
	XM_011534051.2			XP_011532353.1
	XM_011534052.2			XP_011532354.1
	XM_011534053.2			XP_011532355.1
	XM_017007108.1			XP_016862597.1
	XM_017007109.1			XP_016862598.1
	XM_017007110.1			XP_016862599.1
	XM_017007111.1			XP_016862600.1
	XM_017007112.1			XP_016862601.1
	XM_017007113.1			XP_016862602.1
	XM_017007114.1			XP_016862603.1
	XM_017007115.1			XP_016862604.1
	AB307687.1
	AK096628.1
	AY286465.1			AAQ23704.1
	AY286466.1			AAQ23705.1
	AY286467.1			AAQ23706.1
	AY286468.1			AAQ23707.1
	AY286469.1			AAQ23708.1
	AY286470.1			AAQ23709.1
	AY286471.1			AAQ23710.1
	BC106929.1			AAI06930.1
	BC106930.1			AAI06931.1
	BP313943.1
	BQ879477.1
	DA218319.1
	HQ692825.1
	M26747.1			AAA35677.1
	X04707.1			CAA28412.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834639	Chr.3:23995622 - 24192434 on Build GRCh38	Gain	LOC101927854 LINC00691 THRB

More Information

Additional Information:

For this assay, SNP(s) [rs77346389] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
sensory perception of sound
negative regulation of female receptivity
regulation of heart contraction
female courtship behavior
organ morphogenesis
intracellular receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription from RNA polymerase II promoter
Type I pneumocyte differentiation

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription corepressor activity
thyroid hormone receptor activity
protein binding
zinc ion binding
enzyme binding
chromatin DNA binding
sequence-specific DNA binding
thyroid hormone binding