Hs04736923_cn

• Gene Symbol: MCF2L2
• Assay Reference Genome Location: Chr.3:183213697 on build GRCh38
• Cytoband: 3q27.1

Target Gene Details

• Entrez Gene ID: 23101
• Gene Name: MCF.2 cell line derived transforming sequence-like 2
• Gene Aliases: ARHGEF22
• Location: Chr.3:183176116-183428990 on Build GRCh38
• Assay Gene Location: Within Intron 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MCF2L2	NM_015078.3			NP_055893.3
	XM_011512585.2			XP_011510887.1
	XM_011512586.2			XP_011510888.1
	XM_017005943.1			XP_016861432.1
	AB020668.1			BAA74884.1
	AY172737.1			AAO19651.1
	BC029074.2			AAH29074.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893833	Chr.3:183130677 - 183342208 on Build GRCh38	Gain	B3GNT5 LAMP3 MCF2L2
nsv1006872	Chr.3:183194738 - 183548501 on Build GRCh38	Loss	B3GNT5 KLHL6 LINC00888 MCF2L2

More Information

Additional Information:

For this assay, SNP(s) [rs75677427] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

regulation of Rho protein signal transduction
positive regulation of GTPase activity

Function(s)

Rho guanyl-nucleotide exchange factor activity