Hs04941548_cn

• Gene Symbol: HGF
• Assay Reference Genome Location: Chr.7:81700843 on build GRCh38
• Cytoband: 7q21.11

Target Gene Details

• Entrez Gene ID: 3082
• Gene Name: hepatocyte growth factor
• Gene Aliases: DFNB39, F-TCF, HGFB, HPTA, SF
• Location: Chr.7:81699006-81770438 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HGF	NM_000601.5	18	4152	NP_000592.3
	NM_001010932.2	18	4137	NP_001010932.1
	XM_006715956.2	19	4115	XP_006716019.1
	XM_011516115.2	19	4100	XP_011514417.1
	X16323.1	18	4059	CAA34387.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3576398	Chr.7:81685626 - 81732874 on Build GRCh38	Gain	LOC100128317 HGF
nsv1019753	Chr.7:81692852 - 82052256 on Build GRCh38	Gain	CACNA2D1 LOC101927356 HGF

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

activation of MAPK activity
epithelial to mesenchymal transition
liver development
platelet degranulation
proteolysis
mitotic nuclear division
positive regulation of cell proliferation
negative regulation of autophagy
positive regulation of phosphatidylinositol 3-kinase signaling
hyaluronan metabolic process
positive regulation of cell migration
organ regeneration
positive regulation of myelination
negative regulation of interleukin-6 production
positive regulation of interleukin-10 production
negative regulation of peptidyl-serine phosphorylation
cellular response to hepatocyte growth factor stimulus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of osteoblast differentiation
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
hepatocyte growth factor receptor signaling pathway
negative regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
myoblast proliferation
cell chemotaxis
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
positive regulation of neuron projection regeneration
negative regulation of release of cytochrome c from mitochondria
regulation of p38MAPK cascade
negative regulation of hydrogen peroxide-mediated programmed cell death
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of tau-protein kinase activity
positive regulation of DNA biosynthetic process

Function(s)

serine-type endopeptidase activity
protein binding
growth factor activity
chemoattractant activity
protein heterodimerization activity