Hs04968417_cn

• Gene Symbol: TRIM24
• Assay Reference Genome Location: Chr.7:138492583 on build GRCh38
• Cytoband: 7q33

Target Gene Details

• Entrez Gene ID: 8805
• Gene Name: tripartite motif containing 24
• Gene Aliases: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
• Location: Chr.7:138460334-138585588 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM24	NM_003852.3			NP_003843.3
	NM_015905.2			NP_056989.2
	AF009353.1			AAB63585.1
	AF119042.1			AAD17258.1
	AK075306.1
	AK302679.1
	AK312610.1
	BC028689.2			AAH28689.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831153	Chr.7:138393434 - 138580903 on Build GRCh38	Loss	TRIM24
esv34048	Chr.7:138039346 - 138528374 on Build GRCh38	Loss	AKR1D1 TRIM24 MIR4468
esv2735212	Chr.7:138060002 - 140415947 on Build GRCh38	Deletion	TBXAS1 CLEC2L KLRG2 SLC37A3 PARP12 TTC26 AKR1D1 RAB19 ATP6V0A4 LOC100129148 JHDM1D-AS1 LOC105375531 ZC3HAV1 TMEM213 UBN2 ZC3HAV1L HIPK2 SVOPL TRIM24 KDM7A LUC7L2 LOC105375532 KIAA1549 MIR4468 FMC1 C7orf55-LUC7L2
nsv981589	Chr.7:138479101 - 138492710 on Build GRCh38	Duplication	TRIM24
nsv1030956	Chr.7:138478424 - 138894773 on Build GRCh38	Gain	TMEM213 SVOPL TRIM24 ATP6V0A4 KIAA1549

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
negative regulation of cell proliferation
protein ubiquitination
peptidyl-tyrosine phosphorylation
protein catabolic process
regulation of protein stability
regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
protein autophosphorylation
calcium ion homeostasis
regulation of vitamin D receptor signaling pathway
cellular response to estrogen stimulus
regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
chromatin binding
transcription coactivator activity
protein tyrosine kinase activity
ubiquitin-protein transferase activity
receptor binding
protein binding
zinc ion binding
ligase activity
ligand-dependent nuclear receptor binding
estrogen response element binding
methylated histone binding
sequence-specific DNA binding
ubiquitin protein ligase activity
lysine-acetylated histone binding