Hs04993907_cn

• Gene Symbol: TRIM24
• Assay Reference Genome Location: Chr.7:138460329 on build GRCh38
• Cytoband: 7q33

Target Gene Details

• Entrez Gene ID: 8805
• Gene Name: tripartite motif containing 24
• Gene Aliases: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
• Location: Chr.7:138460334-138585588 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM24	NM_003852.3			NP_003843.3
	NM_015905.2			NP_056989.2
	AK075306.1
	AK312610.1	1	124
	CB988362.1	1	100

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831153	Chr.7:138393434 - 138580903 on Build GRCh38	Loss	TRIM24
esv34048	Chr.7:138039346 - 138528374 on Build GRCh38	Loss	AKR1D1 TRIM24 MIR4468
esv2735212	Chr.7:138060002 - 140415947 on Build GRCh38	Deletion	SLC37A3 KIAA1549 LUC7L2 KLRG2 TRIM24 MIR4468 JHDM1D-AS1 TBXAS1 CLEC2L PARP12 UBN2 LOC105375531 TMEM213 SVOPL AKR1D1 KDM7A ZC3HAV1 ZC3HAV1L RAB19 LOC105375532 C7orf55-LUC7L2 HIPK2 TTC26 ATP6V0A4 LOC100129148 FMC1

More Information

Additional Information:

For this assay, SNP(s) [rs182495590] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase II promoter
negative regulation of cell proliferation
protein ubiquitination
peptidyl-tyrosine phosphorylation
protein catabolic process
regulation of protein stability
regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
protein autophosphorylation
calcium ion homeostasis
regulation of vitamin D receptor signaling pathway
cellular response to estrogen stimulus
regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
chromatin binding
transcription coactivator activity
protein tyrosine kinase activity
ubiquitin-protein transferase activity
receptor binding
protein binding
zinc ion binding
ligase activity
ligand-dependent nuclear receptor binding
estrogen response element binding
methylated histone binding
sequence-specific DNA binding
ubiquitin protein ligase activity
lysine-acetylated histone binding