Hs05122136_cn

• Gene Symbol: DNMBP
• Assay Reference Genome Location: Chr.10:99875915 on build GRCh38
• Cytoband: 10q24.2

Target Gene Details

• Entrez Gene ID: 23268
• Gene Name: dynamin binding protein
• Gene Aliases: ARHGEF36, TUBA
• Location: Chr.10:99875571-100009953 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DNMBP	NM_001318326.1	14	5099	NP_001305255.1
	NM_001318327.1	14	3850	NP_001305256.1
	NM_015221.3	17	6096	NP_056036.1
	XM_006717735.2	16	5962	XP_006717798.1
	XM_011539559.2	18	6167	XP_011537861.1
	AA194064.1	1	359
	AA771860.1
	AB023227.1	14	5186	BAA76854.1
	AI023943.1	1	346
	AK128576.1	14	5098
	AL833283.1	17	6062
	BC041628.1	14	3839	AAH41628.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831960	Chr.10:99833844 - 99995448 on Build GRCh38	Gain	ABCC2 DNMBP DNMBP-AS1
nsv825539	Chr.10:99817390 - 99880115 on Build GRCh38	Loss	ABCC2 DNMBP
nsv1046030	Chr.10:99831525 - 99887655 on Build GRCh38	Loss	ABCC2 DNMBP
nsv552045	Chr.10:99862766 - 100074335 on Build GRCh38	Gain	DNMBP DNMBP-AS1 CPN1
nsv825540	Chr.10:99819056 - 99876899 on Build GRCh38	Gain	ABCC2 DNMBP
nsv1046825	Chr.10:99861014 - 99912354 on Build GRCh38	Loss	DNMBP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of GTPase activity

Function(s)

Rho guanyl-nucleotide exchange factor activity
protein binding