Hs05131224_cn

• Gene Symbol: OGDHL
• Assay Reference Genome Location: Chr.10:49741454 on build GRCh38
• Cytoband: 10q11.23

Target Gene Details

• Entrez Gene ID: 55753
• Gene Name: oxoglutarate dehydrogenase-like
• Gene Aliases: -
• Location: Chr.10:49734641-49762379 on Build GRCh38
• Assay Gene Location: Within Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OGDHL	NM_001143996.1			NP_001137468.1
	NM_001143997.1			NP_001137469.1
	NM_018245.2			NP_060715.2
	XM_011539946.1			XP_011538248.1
	XM_011539947.1			XP_011538249.1
	XM_017016401.1			XP_016871890.1
	XM_017016402.1			XP_016871891.1
	XM_017016403.1			XP_016871892.1
	AB033116.3
	AK001713.1			BAA91855.1
	AK225558.1
	AK290226.1
	AK296551.1
	AK303729.1
	BC026320.1			AAH26320.1
	BP209348.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1048905	Chr.10:49720681 - 49811144 on Build GRCh38	Gain	OGDHL
esv3401087	Chr.10:49741400 - 49745098 on Build GRCh38	Duplication	OGDHL
nsv1042677	Chr.10:47993784 - 49928329 on Build GRCh38	Loss	LRRC18 C10orf71-AS1 CHAT ARHGAP22 SLC18A3 FRMPD2 DRGX PGBD3 C10orf53 MAPK8 MIR4294 VSTM4 FAM170B-AS1 ERCC6 C10orf128 FAM25C FAM170B C10orf71 PARG OGDHL AGAP12P WDFY4

More Information

Additional Information:

For this assay, SNP(s) [rs114521070] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase

Gene Ontology Categories:

Process(es)

glycolytic process
tricarboxylic acid cycle

Function(s)

oxoglutarate dehydrogenase (succinyl-transferring) activity
protein binding
thiamine pyrophosphate binding
metal ion binding