Hs05193898_cn

• Gene Symbol: CYP2C18
• Assay Reference Genome Location: Chr.10:94688719 on build GRCh38
• Cytoband: 10q23.33

Target Gene Details

• Entrez Gene ID: 1562
• Gene Name: cytochrome P450 family 2 subfamily C member 18
• Gene Aliases: CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
• Location: Chr.10:94683494-94736190 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP2C18	NM_000772.2			NP_000763.1
	NM_001128925.1			NP_001122397.1
	AK223510.1			BAD97230.1
	AK308558.1
	AK313403.1
	BC069666.1			AAH69666.1
	BC096257.1			AAH96257.1
	BC096258.1			AAH96258.1
	BC096260.1			AAH96260.1
	BX538127.1			CAD98029.1
	M61853.1
	M61856.1			AAB59356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1046308	Chr.10:94681543 - 94873255 on Build GRCh38	Loss	CYP2C19 CYP2C18
esv2672446	Chr.10:94643689 - 94761824 on Build GRCh38	Deletion	CYP2C18
dgv1355n54	Chr.10:94684492 - 94930614 on Build GRCh38	Loss	CYP2C9 CYP2C19 CYP2C18
dgv955n100	Chr.10:94645539 - 94757047 on Build GRCh38	Loss	CYP2C18
nsv522538	Chr.10:94645572 - 94787706 on Build GRCh38	Loss	CYP2C19 CYP2C18
esv2739707	Chr.10:94680312 - 94940071 on Build GRCh38	Deletion	CYP2C9 CYP2C19 CYP2C18
esv3624253	Chr.10:94643661 - 94761810 on Build GRCh38	Loss	CYP2C18
dgv956n100	Chr.10:94657052 - 94726747 on Build GRCh38	Loss	CYP2C18
esv3624254	Chr.10:94644907 - 94724573 on Build GRCh38	Loss	CYP2C18

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, oxygenase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

xenobiotic metabolic process
epoxygenase P450 pathway
oxidation-reduction process

Function(s)

monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
oxygen binding
heme binding
aromatase activity