Hs05196702_cn

• Gene Symbol: DUPD1
• Assay Reference Genome Location: Chr.10:75027296 on build GRCh38
• Cytoband: 10q22.2

Target Gene Details

• Entrez Gene ID: 338599
• Gene Name: dual specificity phosphatase and pro isomerase domain containing 1
• Gene Aliases: DUSP27, FMDSP
• Location: Chr.10:75026427-75073827 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DUPD1	XM_011539747.2			XP_011538049.1

Target Gene Details

• Entrez Gene ID: 23522
• Gene Name: lysine acetyltransferase 6B
• Gene Aliases: GTPTS, MORF, MOZ2, MYST4, ZC2HC6B, qkf, querkopf
• Location: Chr.10:74824927-75032623 on Build GRCh38
• Assay Gene Location: Within Intron 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KAT6B	NM_001256468.1			NP_001243397.1
	NM_001256469.1			NP_001243398.1
	NM_012330.3			NP_036462.2
	XM_005269664.2			XP_005269721.1
	XM_017016000.1			XP_016871489.1
	XM_017016001.1			XP_016871490.1
	XM_017016002.1			XP_016871491.1
	XM_017016003.1			XP_016871492.1
	XM_017016004.1			XP_016871493.1
	XM_017016005.1			XP_016871494.1
	XM_017016006.1			XP_016871495.1
	XM_017016007.1			XP_016871496.1
	XM_017016008.1			XP_016871497.1
	XM_017016009.1			XP_016871498.1
	AB002381.2			BAA20837.2
	AF113514.1			AAF00095.1
	AF119230.1			AAF00099.1
	AF119231.1			AAF00100.1
	AF217500.1			AAL56647.1
	BC021128.1			AAH21128.1
	BC150270.1
	BC150618.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv926n100	Chr.10:74994872 - 75081593 on Build GRCh38	Gain	DUPD1 KAT6B
dgv927n100	Chr.10:75024700 - 75329039 on Build GRCh38	Gain	ZNF503-AS1 COMTD1 SAMD8 ZNF503 DUPD1 DUSP13 KAT6B VDAC2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine dephosphorylation
nucleosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
histone acetylation
histone H3 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter

Function(s)

protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
DNA binding
histone acetyltransferase activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
protein complex binding