Hs05226028_cn

• Gene Symbol: SGPL1
• Assay Reference Genome Location: Chr.10:70821193 on build GRCh38
• Cytoband: 10q22.1

Target Gene Details

• Entrez Gene ID: 8879
• Gene Name: sphingosine-1-phosphate lyase 1
• Gene Aliases: S1PL, SPL
• Location: Chr.10:70815920-70881189 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SGPL1	NM_003901.3			NP_003892.2
	XM_005270263.1			XP_005270320.1
	XM_006718053.1			XP_006718116.1
	XM_011540316.2			XP_011538618.1
	XM_011540317.1			XP_011538619.1
	XM_011540318.1			XP_011538620.1
	AB033078.1
	AF144638.1			AAD44755.1
	AJ011304.2			CAA09590.2
	AK314615.1
	BC052991.1			AAH52991.1
	BP314104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1043245	Chr.10:70290210 - 70915897 on Build GRCh38	Loss	NODAL PCBD1 PALD1 ADAMTS14 SGPL1 PRF1 TBATA LRRC20 EIF4EBP2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

luteinization
vasculogenesis
kidney development
fatty acid metabolic process
ceramide metabolic process
spermatogenesis
androgen metabolic process
estrogen metabolic process
post-embryonic development
fibroblast migration
hemopoiesis
sphingolipid biosynthetic process
sphingolipid catabolic process
Leydig cell differentiation
regulation of multicellular organism growth
platelet-derived growth factor receptor signaling pathway
skeletal system morphogenesis
palate development
face morphogenesis
apoptotic signaling pathway

Function(s)

protein binding
sphinganine-1-phosphate aldolase activity
carboxy-lyase activity
pyridoxal phosphate binding