Hs05243323_cn

• Gene Symbol: APLP2
• Assay Reference Genome Location: Chr.11:130089112 on build GRCh38
• Cytoband: 11q24.3

Target Gene Details

• Entrez Gene ID: 334
• Gene Name: amyloid beta precursor like protein 2
• Gene Aliases: APLP-2, APPH, APPL2, CDEBP
• Location: Chr.11:130069821-130144811 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
APLP2	NM_001142276.1			NP_001135748.1
	NM_001142277.1			NP_001135749.1
	NM_001142278.1			NP_001135750.1
	NM_001243299.1			NP_001230228.1
	NM_001642.2			NP_001633.1
	NR_024515.1
	NR_024516.1
	AF168956.1			AAD47291.1
	AK056883.1
	AK128162.1
	AK225283.1
	AK296765.1
	AK300378.1
	AK304736.1
	AK308248.1
	BC000373.2			AAH00373.1
	BC004371.1			AAH04371.1
	DC336210.1
	L09209.1			AAA35526.1
	L19597.1			AAA35601.1
	L27631.1			AAC41701.1
	S60099.1			AAC60589.1
	Z22572.1			CAA80295.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3579969	Chr.11:130079603 - 130093108 on Build GRCh38	Loss	APLP2
nsv556565	Chr.11:129996758 - 130180927 on Build GRCh38	Loss	ST14 PRDM10 LINC00167 APLP2
dgv251n67	Chr.11:130005191 - 130124741 on Build GRCh38	Gain	LINC00167 APLP2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

platelet degranulation
G-protein coupled receptor signaling pathway
negative regulation of endopeptidase activity

Function(s)

DNA binding
serine-type endopeptidase inhibitor activity
protein binding
heparin binding
identical protein binding
transition metal ion binding