Hs05336091_cn

• Gene Symbol: USP8
• Assay Reference Genome Location: Chr.15:50440259 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 9101
• Gene Name: ubiquitin specific peptidase 8
• Gene Aliases: HumORF8, SPG59, UBPY
• Location: Chr.15:50424359-50501083 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
USP8	NM_001128610.2			NP_001122082.1
	NM_001283049.1			NP_001269978.1
	NM_005154.4			NP_005145.3
	XM_006720761.3			XP_006720824.1
	XM_006720762.3			XP_006720825.1
	XM_011522193.2			XP_011520495.1
	XM_017022718.1			XP_016878207.1
	XM_017022719.1			XP_016878208.1
	XM_017022720.1			XP_016878209.1
	XM_017022721.1			XP_016878210.1
	XM_017022722.1			XP_016878211.1
	AK292400.1
	AK296480.1
	BC015545.1
	BC026954.1
	BC038801.1			AAH38801.1
	BC051345.1			AAH51345.1
	BC110590.2			AAI10591.1
	BX537420.1			CAD97662.1
	D29956.1
	DA112964.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv524613	Chr.15:50364252 - 50576582 on Build GRCh38	Loss	USP50 TRPM7 USP8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
ubiquitin-dependent protein catabolic process
endosome organization
cell proliferation
protein deubiquitination
ERBB2 signaling pathway
protein K63-linked deubiquitination
protein K48-linked deubiquitination
cell-cell adhesion

Function(s)

cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
SH3 domain binding
cadherin binding involved in cell-cell adhesion