Hs05387278_cn

• Gene Symbol: GNB5
• Assay Reference Genome Location: Chr.15:52137877 on build GRCh38
• Cytoband: 15q21.2

Target Gene Details

• Entrez Gene ID: 10681
• Gene Name: G protein subunit beta 5
• Gene Aliases: GB5
• Location: Chr.15:52120926-52191368 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GNB5	NM_006578.3			NP_006569.1
	NM_016194.3			NP_057278.2
	XM_011521162.2			XP_011519464.1
	XM_011521163.2			XP_011519465.1
	XM_017021867.1			XP_016877356.1
	AF017656.1			AAC63826.1
	AF300650.1			AAG18444.1
	AF501885.1			AAM15921.1
	AK125702.1	2	211
	AK290330.1
	AK314775.1
	AL117471.1			CAB55946.1
	BC013997.2			AAH13997.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1047647	Chr.15:52133682 - 52176984 on Build GRCh38	Gain	GNB5
nsv471244	Chr.15:52013266 - 52219268 on Build GRCh38	Gain	GNB5 MAPK6 LOC100129973 BCL2L10 MYO5C
nsv833005	Chr.15:52097672 - 52249133 on Build GRCh38	Gain	GNB5 LOC100129973 BCL2L10 MYO5C
esv2571437	Chr.15:52137269 - 52138722 on Build GRCh38	Deletion	GNB5

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

heterotrimeric G-protein

Gene Ontology Categories:

Process(es)

protein folding
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
negative regulation of voltage-gated calcium channel activity

Function(s)

GTPase activity
signal transducer activity
GTPase activator activity
protein binding
G-protein gamma-subunit binding
chaperone binding