Hs05396849_cn

• Gene Symbol: CDH15
• Assay Reference Genome Location: Chr.16:89176585 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 1013
• Gene Name: cadherin 15
• Gene Aliases: CDH14, CDH3, CDHM, MCAD, MRD3
• Location: Chr.16:89171755-89195492 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDH15	NM_004933.2			NP_004924.1
	AK308596.1
	AK308631.1
	BC008951.2			AAH08951.1
	D83542.1			BAA12012.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509638	Chr.16:89152681 - 89296203 on Build GRCh38	Insertion	CDH15 LOC105371414 LINC00304 SLC22A31 LOC400558 ZNF778 ANKRD11 ACSF3
nsv952072	Chr.16:89032193 - 89201992 on Build GRCh38	Deletion	CDH15 LINC00304 SLC22A31 LOC400558 ACSF3
nsv573727	Chr.16:89169527 - 89193067 on Build GRCh38	Loss	CDH15
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC100129697 CDH15 APRT SLC22A31 PABPN1L ZNF778 PIEZO1 LOC105371409 CBFA2T3 CDT1 LOC339059 CTU2 LOC101927793 LINC00304 LOC107987238 LOC400558 TRAPPC2L MIR4722 LOC100289580 ACSF3 GALNS
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC100129697 CDH15 APRT SLC22A31 PABPN1L LOC105371409 CBFA2T3 CDT1 LOC101927793 LINC00304 LOC107987238 LOC400558 TRAPPC2L ACSF3 GALNS
nsv573720	Chr.16:88968841 - 89184474 on Build GRCh38	Gain	CDH15 LINC00304 LOC400558 ACSF3 CBFA2T3
nsv573724	Chr.16:89100686 - 89217401 on Build GRCh38	Loss	CDH15 LINC00304 SLC22A31 LOC400558 ZNF778 ACSF3
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC100129697 CDH15 APRT LOC105371414 SLC22A31 PABPN1L ZNF778 PIEZO1 ANKRD11 LOC105371409 CBFA2T3 CDT1 LOC339059 LOC100287036 LOC101927793 LINC00304 LOC107987238 LOC400558 TRAPPC2L LOC100289580 ACSF3 GALNS
dgv3066n100	Chr.16:89067685 - 89301626 on Build GRCh38	Gain	CDH15 LOC105371414 LINC00304 SLC22A31 LOC400558 ZNF778 ANKRD11 ACSF3
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	VPS9D1-AS1 GAS8-AS1 PABPN1L LOC105371419 VPS9D1 CDK10 CDT1 MC1R TUBB8P7 CHMP1A FANCA RNF166 APRT CPNE7 ZNF778 PRDM7 DPEP1 LOC105371409 TUBB3 SNAI3 SPG7 ZNF276 LOC100287036 CTU2 LOC107987238 FAM157C MVD SPATA33 DBNDD1 LOC100129697 LOC107984817 SNORD68 SNAI3-AS1 CDH15 LOC105371414 SLC22A31 IL17C PIEZO1 ANKRD11 CBFA2T3 URAHP CENPBD1 LOC339059 AFG3L1P LINC00304 LOC400558 TRAPPC2L RPL13 MIR4722 GALNS GAS8 SPATA2L TCF25 LOC101927817 LOC101927793 CYBA SPIRE2 DEF8 LOC100289580 ACSF3
dgv5320n54	Chr.16:89114475 - 89197443 on Build GRCh38	Loss	CDH15 LINC00304 SLC22A31 LOC400558 ACSF3

More Information

Additional Information:

For this assay, SNP(s) [rs72819356] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cadherin

Gene Ontology Categories:

Process(es)

cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
adherens junction organization
positive regulation of muscle cell differentiation

Function(s)

calcium ion binding
protein binding