Hs05408214_cn

• Gene Symbol: HMOX2
• Assay Reference Genome Location: Chr.16:4479442 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 3163
• Gene Name: heme oxygenase 2
• Gene Aliases: HO-2
• Location: Chr.16:4474697-4510347 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HMOX2	NM_001127204.1			NP_001120676.1
	NM_001127206.2			NP_001120678.1
	NM_001286267.1			NP_001273196.1
	NM_001286268.1			NP_001273197.1
	NM_001286269.1			NP_001273198.1
	NM_001286271.1			NP_001273200.1
	NM_002134.3			NP_002125.3
	XM_017023196.1			XP_016878685.1
	XM_017023197.1			XP_016878686.1
	AK222629.1			BAD96349.1
	AK313660.1
	BC002396.2			AAH02396.1
	BE561721.1
	BI225653.1
	BM905872.1
	BP329113.1
	DA141643.1
	DA694137.1
	DB184091.1
	S34389.1			AAB22110.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1160332	Chr.16:4367643 - 4486554 on Build GRCh38	Duplication	CORO7 CORO7-PAM16 NMRAL1 HMOX2 DNAJA3 VASN
nsv1046986	Chr.16:4049000 - 5555721 on Build GRCh38	Gain	SEPT12 MGRN1 NMRAL1 UBN1 DNAJA3 GLIS2-AS1 C16orf89 CDIP1 UBALD1 CORO7 PAM16 ZNF500 ALG1 SMIM22 PPL C16orf96 NAGPA CORO7-PAM16 MIR6769A HMOX2 C16orf71 NAGPA-AS1 SEC14L5 EEF2KMT ANKS3 ROGDI LOC105371063 NUDT16L1 LINC01569 GLYR1 RBFOX1 SRL GLIS2 VASN TFAP4 ADCY9

More Information

Additional Information:

For this assay, SNP(s) [rs118181434] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

response to hypoxia
heme oxidation
cellular iron ion homeostasis
heme catabolic process

Function(s)

heme oxygenase (decyclizing) activity
protein binding
metal ion binding