Hs05514586_cn

• Gene Symbol: SLC16A3
• Assay Reference Genome Location: Chr.17:82230826 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 9123
• Gene Name: solute carrier family 16 member 3
• Gene Aliases: MCT 3, MCT 4, MCT-3, MCT-4, MCT3, MCT4
• Location: Chr.17:82228406-82239499 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLC16A3	NM_001042422.2			NP_001035887.1
	NM_001206950.1			NP_001193879.1
	NM_004207.3			NP_004198.1
	AK223040.1			BAD96760.1
	BM926587.1
	DA419716.1
	DA583988.1
	U81800.1			AAC52015.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv2166	Chr.17:82212292 - 82238972 on Build GRCh38	Insertion	MIR6787 SLC16A3 CCDC57
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	PYCR1 FN3K DCXR DUS1L FOXK2 PPP1R27 MYADML2 ZNF750 GCGR TMEM105 SLC25A10 ALYREF WDR45B UTS2R LOC105371925 P4HB TEPSIN RFNG GPS1 SLC16A3 MIR4525 CCDC57 NPLOC4 MIR6786 MIR6787 LOC105376791 LOC101929511 LRRC45 MIR3186 STRA13 ARL16 NOTUM NPB C17orf62 FSCN2 AATK-AS1 ARHGDIA SNORD134 CEP131 RAB40B LOC101929552 MAFG-AS1 B3GNTL1 MAFG ACTG1 AATK TEX19 FASN ANAPC11 C17orf89 MCRIP1 LOC105371944 NARF ASPSCR1 OXLD1 MRPL12 CCDC137 PCYT2 PDE6G LOC100130370 BAHCC1 HEXDC MIR4740 TSPAN10 CSNK1D RAC3 LOC105376790 LINC00482 SLC38A10 OGFOD3 TBCD SIRT7 FAAP100 FN3KRP CD7 SECTM1 HGS
nsv576193	Chr.17:82226048 - 82237706 on Build GRCh38	Loss	MIR6787 SLC16A3
nsv833572	Chr.17:82204977 - 82388835 on Build GRCh38	Loss	MIR6787 LOC101929511 CSNK1D UTS2R CD7 LOC105376790 TEX19 SECTM1 SLC16A3 CCDC57
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	PYCR1 FN3K DCXR DUS1L FOXK2 PPP1R27 MYADML2 ZNF750 ALYREF WDR45B UTS2R P4HB RFNG GPS1 SLC16A3 MIR4525 CCDC57 MIR6787 LOC105376791 LOC101929511 LRRC45 STRA13 METRNL NOTUM NPB C17orf62 ARHGDIA SNORD134 RAB40B LOC101929552 MAFG-AS1 B3GNTL1 MAFG TEX19 FASN ANAPC11 MCRIP1 LOC105371944 NARF ASPSCR1 PCYT2 HEXDC CSNK1D RAC3 LOC105376790 OGFOD3 TBCD SIRT7 FN3KRP CD7 SECTM1

More Information

Additional Information:

For this assay, SNP(s) [rs116990655] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transporter

Gene Ontology Categories:

Process(es)

pyruvate metabolic process
monocarboxylic acid transport
plasma membrane lactate transport
leukocyte migration

Function(s)

protein binding
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
poly(A) RNA binding