Hs05571846_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37133259 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3			NP_000869.1
	AK312860.1
	BC025691.1			AAH25691.1
	CR456506.1			CAG30392.1
	M26062.1			AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	LOC102724378 MPST MFNG CARD10 TMPRSS6 GGA1 SH3BP1 TRIOBP C1QTNF6 NOL12 LGALS2 LGALS1 LOC100506271 TST CYTH4 TEX33 PDXP SSTR3 RAC2 KCTD17 LOC101927051 ELFN2 CDC42EP1 IL2RB
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	MPST TST LL22NC01-81G9.3 TEX33 TMPRSS6 KCTD17 IL2RB
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	MPST TST LL22NC01-81G9.3 TEX33 TMPRSS6 C1QTNF6 KCTD17 IL2RB
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	MPST TST LL22NC01-81G9.3 TEX33 TMPRSS6 KCTD17 IL2RB

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding