Hs05573680_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37135872 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3			NP_000869.1
	AK312860.1
	BC025691.1			AAH25691.1
	CR456506.1			CAG30392.1
	M26062.1			AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	KCTD17 TMPRSS6 LGALS2 MFNG TRIOBP LOC102724378 LOC101927051 TST IL2RB PDXP LGALS1 ELFN2 SSTR3 TEX33 SH3BP1 CDC42EP1 CYTH4 MPST CARD10 GGA1 RAC2 C1QTNF6 LOC100506271 NOL12
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	KCTD17 TMPRSS6 MPST TST IL2RB LL22NC01-81G9.3 TEX33
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	KCTD17 TMPRSS6 MPST TST IL2RB LL22NC01-81G9.3 C1QTNF6 TEX33
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	KCTD17 TMPRSS6 MPST TST IL2RB LL22NC01-81G9.3 TEX33
nsv588986	Chr.22:37133758 - 37145791 on Build GRCh38	Gain	IL2RB

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding