Hs05581626_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37130628 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3			NP_000869.1
	AK312860.1
	BC025691.1			AAH25691.1
	CR456506.1			CAG30392.1
	M26062.1			AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	ELFN2 C1QTNF6 PDXP CARD10 RAC2 KCTD17 SH3BP1 LGALS2 LOC101927051 IL2RB TST MPST MFNG LGALS1 TMPRSS6 TRIOBP TEX33 CYTH4 SSTR3 LOC102724378 NOL12 CDC42EP1 LOC100506271 GGA1
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	IL2RB TST MPST TMPRSS6 TEX33 KCTD17 LL22NC01-81G9.3
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	IL2RB TST MPST C1QTNF6 TMPRSS6 TEX33 KCTD17 LL22NC01-81G9.3
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	IL2RB TST MPST TMPRSS6 TEX33 KCTD17 LL22NC01-81G9.3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding