Hs05583865_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37129966 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3			NP_000869.1
	AK312860.1
	BC025691.1			AAH25691.1
	CR456506.1			CAG30392.1
	M26062.1			AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	TMPRSS6 NOL12 LOC100506271 MFNG LGALS1 KCTD17 GGA1 SH3BP1 TRIOBP LOC101927051 CARD10 LOC102724378 PDXP SSTR3 CYTH4 IL2RB ELFN2 TST LGALS2 CDC42EP1 MPST TEX33 C1QTNF6 RAC2
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	TMPRSS6 LL22NC01-81G9.3 IL2RB TST KCTD17 MPST TEX33
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	TMPRSS6 LL22NC01-81G9.3 IL2RB TST KCTD17 MPST TEX33 C1QTNF6
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	TMPRSS6 LL22NC01-81G9.3 IL2RB TST KCTD17 MPST TEX33

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding