Hs05720005_cn

• Gene Symbol: AGO3
• Assay Reference Genome Location: Chr.1:35965092 on build GRCh38
• Cytoband: 1p34.3

Target Gene Details

• Entrez Gene ID: 192669
• Gene Name: argonaute 3, RISC catalytic component
• Gene Aliases: EIF2C3
• Location: Chr.1:35925198-36072037 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGO3	NM_024852.3			NP_079128.2
	NM_177422.2			NP_803171.1
	XM_005270575.3			XP_005270632.1
	XM_011540879.2			XP_011539181.1
	XM_017000523.1			XP_016856012.1
	AK022827.1			BAB14262.1
	AK027796.1			BAB55374.1
	AK292870.1
	BC066888.1			AAH66888.1
	BF979526.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998713	Chr.1:35956942 - 36008597 on Build GRCh38	Gain	AGO3
dgv149n100	Chr.1:35947159 - 36032074 on Build GRCh38	Loss	AGO3
nsv1009992	Chr.1:35949901 - 36009793 on Build GRCh38	Gain+Loss	AGO3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

translation initiation factor

Gene Ontology Categories:

Process(es)

mRNA catabolic process
Wnt signaling pathway, calcium modulating pathway
RNA secondary structure unwinding
pre-miRNA processing
posttranscriptional gene silencing by RNA
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
phosphatidylinositol-mediated signaling
regulation of stem cell proliferation
mRNA cleavage involved in gene silencing by siRNA

Function(s)

double-stranded RNA binding
single-stranded RNA binding
protein binding
miRNA binding
poly(A) RNA binding