Hs05733871_cn

• Gene Symbol: PIK3R3
• Assay Reference Genome Location: Chr.1:46175085 on build GRCh38
• Cytoband: 1p34.1

Target Gene Details

• Entrez Gene ID: 8503
• Gene Name: phosphoinositide-3-kinase regulatory subunit 3
• Gene Aliases: p55, p55-GAMMA, p55PIK
• Location: Chr.1:46040140-46176495 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIK3R3	NM_001303427.1			NP_001290356.1
	AK302049.1
	DB047431.1

Target Gene Details

• Entrez Gene ID: 10103
• Gene Name: tetraspanin 1
• Gene Aliases: NET1, TM4C, TM4SF
• Location: Chr.1:46175077-46196489 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TSPAN1	NM_005727.3			NP_005718.2
	XM_011540460.2			XP_011538762.1
	AK313774.1
	BM908049.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2761743	Chr.1:45874186 - 46561071 on Build GRCh38	Gain	LOC101929626 UQCRH FAAH KNCN MKNK1 TSPAN1 MAST2 LRRC41 DMBX1 LINC01398 POMGNT1 RAD54L MKNK1-AS1 NSUN4 PIK3R3 LURAP1 FAAHP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

phosphatidylinositol biosynthetic process
insulin receptor signaling pathway
phosphatidylinositol-3-phosphate biosynthetic process
regulation of phosphatidylinositol 3-kinase activity
positive regulation of glucose import in response to insulin stimulus
cell surface receptor signaling pathway
cell proliferation
cell migration
positive regulation of endocytosis
protein stabilization

Function(s)

protein binding
1-phosphatidylinositol-3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity