Hs05788226_cn

• Gene Symbol: KCNN3
• Assay Reference Genome Location: Chr.1:154702843 on build GRCh38
• Cytoband: 1q21.3

Target Gene Details

• Entrez Gene ID: 3782
• Gene Name: potassium calcium-activated channel subfamily N member 3
• Gene Aliases: KCa2.3, SK3, SKCA3, hSK3
• Location: Chr.1:154697462-154870278 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
KCNN3	NM_001204087.1	9	7688	NP_001191016.1
	NM_002249.5	8	7643	NP_002240.3
	NM_170782.2	8	6564	NP_740752.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509491	Chr.1:154692639 - 154719309 on Build GRCh38	Insertion	KCNN3
nsv521887	Chr.1:154264094 - 154711630 on Build GRCh38	Gain	KCNN3 TDRD10 ATP8B2 SHE UBE2Q1 HAX1 IL6R CHRNB2 AQP10 UBAP2L LOC101928101 UBE2Q1-AS1 ADAR
nsv547958	Chr.1:154596207 - 154828771 on Build GRCh38	Gain	KCNN3 ADAR

More Information

Additional Information:

For this assay, SNP(s) [rs73003213] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

voltage-gated ion channel

Gene Ontology Categories:

Process(es)

potassium ion transmembrane transport
positive regulation of protein targeting to mitochondrion

Function(s)

calmodulin binding
small conductance calcium-activated potassium channel activity