Hs05801814_cn

• Gene Symbol: RPS6KA1
• Assay Reference Genome Location: Chr.1:26544145 on build GRCh38
• Cytoband: 1p36.11

Target Gene Details

• Entrez Gene ID: 6195
• Gene Name: ribosomal protein S6 kinase A1
• Gene Aliases: HU-1, MAPKAPK1A, RSK, RSK1, p90Rsk
• Location: Chr.1:26529758-26575029 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RPS6KA1	NM_002953.3			NP_002944.2
	XM_005245966.4			XP_005246023.1
	AK225672.1
	AK294818.1
	AK299007.1
	AK315730.1
	BC014966.1			AAH14966.1
	BM836865.1
	L07597.1			AAC82497.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526179	Chr.1:26534790 - 26579076 on Build GRCh38	Gain	RPS6KA1 MIR1976
nsv545908	Chr.1:26509300 - 26661535 on Build GRCh38	Loss	RPS6KA1 MIR1976

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein phosphorylation
apoptotic process
cell cycle
signal transduction
positive regulation of cell growth
intracellular signal transduction
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of translation in response to stress
regulation of DNA-templated transcription in response to stress
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
hepatocyte proliferation
positive regulation of hepatic stellate cell activation

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein binding
ATP binding
kinase activity
cysteine-type endopeptidase inhibitor activity involved in apoptotic process