Hs05835289_cn

• Gene Symbol: ANAPC1
• Assay Reference Genome Location: Chr.2:111868952 on build GRCh38
• Cytoband: 2q13

Target Gene Details

• Entrez Gene ID: 64682
• Gene Name: anaphase promoting complex subunit 1
• Gene Aliases: APC1, MCPR, TSG24
• Location: Chr.2:111766147-111884196 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC1	NM_022662.3			NP_073153.1
	XM_011511633.2			XP_011509935.1
	XM_011511634.2			XP_011509936.1
	XM_011511636.2			XP_011509938.1
	XM_011511637.2			XP_011509939.1
	XM_017004710.1			XP_016860199.1
	XM_017004711.1			XP_016860200.1
	XM_017004712.1			XP_016860201.1
	XM_017004713.1			XP_016860202.1
	XM_017004714.1			XP_016860203.1
	XM_017004715.1			XP_016860204.1
	AJ278357.1			CAC19484.1
	BC104902.1			AAI04903.1
	BC104904.1			AAI04905.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv961487	Chr.2:111867857 - 111875358 on Build GRCh38	Duplication	ANAPC1
esv26491	Chr.2:111835916 - 111883720 on Build GRCh38	Gain	ANAPC1
nsv582699	Chr.2:110763166 - 112172487 on Build GRCh38	Loss	TMEM87B FBLN7 PAFAH1B1P2 MIR4435-2 MIR4771-2 ANAPC1 MIR4435-2HG MERTK LOC400997 BCL2L11 ACOXL
nsv521956	Chr.2:110634682 - 112341235 on Build GRCh38	Loss	ZC3H6 MIR4771-2 MIR4435-2HG ZC3H8 LOC400997 TMEM87B FBLN7 SNORD132 PAFAH1B1P2 MIR4435-2 ANAPC1 MERTK BUB1 BCL2L11 ACOXL
nsv834333	Chr.2:111732634 - 111900770 on Build GRCh38	Gain	MIR4771-2 ANAPC1 MERTK
nsv428402	Chr.2:111142206 - 111905020 on Build GRCh38	Loss	PAFAH1B1P2 MIR4435-2 MIR4771-2 ANAPC1 MIR4435-2HG MERTK BCL2L11
dgv4047n100	Chr.2:110308696 - 112358403 on Build GRCh38	Loss	LOC105375809 LINC01106 ZC3H6 RGPD6 MIR4771-2 MIR4435-2HG ZC3H8 LOC400997 LOC105373553 LIMS4 TMEM87B FBLN7 SNORD132 PAFAH1B1P2 MIR4435-2 ANAPC1 LOC100288570 MERTK BUB1 BCL2L11 ACOXL

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination