Hs05840421_cn

• Gene Symbol: ACKR3
• Assay Reference Genome Location: Chr.2:236567511 on build GRCh38
• Cytoband: 2q37.3

Target Gene Details

• Entrez Gene ID: 57007
• Gene Name: atypical chemokine receptor 3
• Gene Aliases: CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1
• Location: Chr.2:236537131-236582358 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ACKR3	XM_005246098.3			XP_005246155.1
	XM_017004516.1			XP_016860005.1
	BC036661.2			AAH36661.1
	DB455412.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1005677	Chr.2:236369512 - 236811991 on Build GRCh38	Gain	IQCA1 LOC105373991 ACKR3
nsv1073025	Chr.2:236567456 - 236568357 on Build GRCh38	Deletion	LOC105373991 ACKR3
nsv997438	Chr.2:236210757 - 237034862 on Build GRCh38	Gain	ASB18 IQCA1 LOC105373991 ACKR3
nsv1000252	Chr.2:235899999 - 238766417 on Build GRCh38	Loss	LOC105373944 ASB18 AGAP1 RBM44 ASB1 GBX2 MLPH LOC643387 TRAF3IP1 SCLY ESPNL RAB17 PRLH LOC105373958 LOC101927958 IQCA1 MIR6811 RAMP1 LOC105373991 LOC93463 ACKR3 LINC01107 ILKAP HES6 COL6A3 LRRFIP1 KLHL30 UBE2F-SCLY PER2 LOC151174 UBE2F ERFE COPS8
nsv834576	Chr.2:236466567 - 236654210 on Build GRCh38	Gain	IQCA1 LOC105373991 ACKR3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

angiogenesis
vasculogenesis
positive regulation of defense response to virus by host
chemotaxis
cell adhesion
G-protein coupled receptor signaling pathway
viral process
receptor internalization
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
xenophagy
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Function(s)

scavenger receptor activity
protein binding
coreceptor activity
C-X-C chemokine receptor activity
C-X-C chemokine binding