Hs05869255_cn

• Gene Symbol: LIMS1
• Assay Reference Genome Location: Chr.2:108537909 on build GRCh38
• Cytoband: 2q12.3

Target Gene Details

• Entrez Gene ID: 3987
• Gene Name: LIM zinc finger domain containing 1
• Gene Aliases: PINCH, PINCH-1, PINCH1
• Location: Chr.2:108534355-108687246 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LIMS1	NM_001193483.2			NP_001180412.1
	XM_005263949.1			XP_005264006.1
	XM_017004092.1			XP_016859581.1
	AF527761.1
	AK296992.1
	AK314217.1
	DC401794.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759081	Chr.2:107833421 - 108606881 on Build GRCh38	Gain	LINC01594 SULT1C2P1 SULT1C4 LIMS1 SULT1C2 GCC2-AS1 RGPD4 SLC5A7 LINC01593 GCC2 SULT1C3
nsv834328	Chr.2:108422875 - 108613866 on Build GRCh38	Gain	LIMS1 GCC2-AS1 GCC2
esv2720498	Chr.2:107831020 - 108722824 on Build GRCh38	Deletion	LINC01594 SULT1C2P1 SULT1C4 LIMS1 SULT1C2 RANBP2 GCC2-AS1 RGPD4 SLC5A7 LINC01593 GCC2 SULT1C3
nsv527491	Chr.2:107924531 - 108650418 on Build GRCh38	Loss	LINC01594 SULT1C2P1 SULT1C4 LIMS1 SULT1C2 GCC2-AS1 SLC5A7 LINC01593 GCC2 SULT1C3

More Information

Additional Information:

For this assay, SNP(s) [rs149401518] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cell junction protein

Gene Ontology Categories:

Process(es)

epithelial to mesenchymal transition
cell aging
positive regulation of gene expression
positive regulation of cell-substrate adhesion
cell junction assembly
positive regulation of GTPase activity
establishment of protein localization
negative regulation of transcription, DNA-templated
regulation of epithelial cell proliferation
positive regulation of focal adhesion assembly
cellular response to transforming growth factor beta stimulus
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

protein binding
zinc ion binding
protein kinase binding