Hs05901658_cn

• Gene Symbol: LARS2
• Assay Reference Genome Location: Chr.3:45509130 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 23395
• Gene Name: leucyl-tRNA synthetase 2, mitochondrial
• Gene Aliases: LEURS, PRLTS4, mtLeuRS
• Location: Chr.3:45388561-45548842 on Build GRCh38
• Assay Gene Location: Within Intron 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LARS2	NM_015340.3			NP_056155.1
	XM_005265006.1			XP_005265063.1
	XM_011533554.2			XP_011531856.1
	XM_017006042.1			XP_016861531.1
	AK025465.1
	AK026113.1
	AK308146.1
	BC025989.2			AAH25989.1
	D21851.1

Target Gene Details

• Entrez Gene ID: 100885795
• Gene Name: LARS2 antisense RNA 1
• Gene Aliases: -
• Location: Chr.3:45482695-45509545 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LARS2-AS1	NR_048543.1
	DB017595.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv8301n54	Chr.3:45507536 - 45509980 on Build GRCh38	Loss	LARS2-AS1 LARS2
esv25561	Chr.3:45501795 - 45510572 on Build GRCh38	Loss	LARS2-AS1 LARS2
dgv8303n54	Chr.3:45507806 - 45514461 on Build GRCh38	Loss	LARS2-AS1 LARS2
nsv590177	Chr.3:45508299 - 45509915 on Build GRCh38	Loss	LARS2-AS1 LARS2
esv3561814	Chr.3:45501509 - 45510579 on Build GRCh38	Deletion	LARS2-AS1 LARS2
esv2664866	Chr.3:45501801 - 45510566 on Build GRCh38	Deletion	LARS2-AS1 LARS2
nsv834677	Chr.3:45343270 - 45511215 on Build GRCh38	Gain	LARS2-AS1 LARS2
nsv590162	Chr.3:45500591 - 45510525 on Build GRCh38	Loss	LARS2-AS1 LARS2

More Information

Additional Information:

For this assay, SNP(s) [rs374367931] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
leucyl-tRNA aminoacylation
regulation of translational fidelity

Function(s)

aminoacyl-tRNA editing activity
leucine-tRNA ligase activity
ATP binding