Hs05997275_cn

• Gene Symbol: TNIP1
• Assay Reference Genome Location: Chr.5:151032723 on build GRCh38
• Cytoband: 5q33.1

Target Gene Details

• Entrez Gene ID: 10318
• Gene Name: TNFAIP3 interacting protein 1
• Gene Aliases: ABIN-1, NAF1, VAN, nip40-1
• Location: Chr.5:151029943-151087660 on Build GRCh38
• Assay Gene Location: Within Intron 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNIP1	NM_001252385.1			NP_001239314.1
	NM_001252386.1			NP_001239315.1
	NM_001252390.1			NP_001239319.1
	NM_001252391.1			NP_001239320.1
	NM_001252392.1			NP_001239321.1
	NM_001252393.1			NP_001239322.1
	NM_001258454.1			NP_001245383.1
	NM_001258455.1			NP_001245384.1
	NM_001258456.1			NP_001245385.1
	NM_006058.4			NP_006049.3
	XM_005268355.1			XP_005268412.1
	XM_006714751.1			XP_006714814.1
	XM_006714752.2			XP_006714815.1
	XM_017008945.1			XP_016864434.1
	XM_017008946.1			XP_016864435.1
	XM_017008947.1			XP_016864436.1
	XM_017008948.1			XP_016864437.1
	XM_017008949.1			XP_016864438.1
	XM_017008950.1			XP_016864439.1
	XM_017008951.1			XP_016864440.1
	AB177543.1
	AB177544.1
	AB252970.1
	AB252971.1
	AB252972.1
	AB252973.1
	AB252976.1
	AB252977.1
	AB252978.1
	AB252979.1
	AB252980.1
	AB252981.1
	AB252982.1
	AJ011895.1			CAA09855.1
	AJ011896.1			CAA09856.1
	AK074400.1
	AK097213.1	1	134
	AK290999.1
	AK298685.1
	AK299975.1
	AK303573.1
	AY012155.1			AAG42154.1
	BC012133.1			AAH12133.1
	BC014008.1			AAH14008.1
	BX640647.1			CAE45793.1
	D30755.2			BAA06416.2
	U39403.1			AAC99999.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv526224	Chr.5:151003841 - 151070675 on Build GRCh38	Gain	GPX3 TNIP1

More Information

Additional Information:

For this assay, SNP(s) [rs78001506] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

MyD88-dependent toll-like receptor signaling pathway
translation
proteolysis
defense response
inflammatory response
leukocyte cell-cell adhesion
glycoprotein biosynthetic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of viral genome replication
positive regulation of transcription from RNA polymerase II promoter
positive regulation of inflammatory response
negative regulation of ERK1 and ERK2 cascade
modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
mitogen-activated protein kinase binding