Hs06024620_cn

• Gene Symbol: POLK
• Assay Reference Genome Location: Chr.5:75539290 on build GRCh38
• Cytoband: 5q13.3

Target Gene Details

• Entrez Gene ID: 51426
• Gene Name: polymerase (DNA) kappa
• Gene Aliases: DINB1, DINP, POLQ
• Location: Chr.5:75511832-75602576 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLK	NM_016218.2			NP_057302.1
	XM_005248534.4			XP_005248591.1
	XM_011543463.2			XP_011541765.1
	XM_011543464.2			XP_011541766.1
	XM_011543467.2			XP_011541769.1
	XM_017009559.1			XP_016865048.1
	XM_017009561.1			XP_016865050.1
	XM_017009562.1			XP_016865051.1
	XM_017009563.1			XP_016865052.1
	XM_017009564.1			XP_016865053.1
	AF163570.1			AAF02540.1
	AF194973.1			AAF23270.1
	AF318313.1			AAN15781.1
	AK091659.1			BAC03714.1
	AK314610.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3605448	Chr.5:75534375 - 75540313 on Build GRCh38	Loss	POLK
esv3570200	Chr.5:75533942 - 75543482 on Build GRCh38	Loss	POLK

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
error-prone translesion synthesis

Function(s)

damaged DNA binding
DNA-directed DNA polymerase activity
metal ion binding