Hs06105767_cn

• Gene Symbol: SKP2
• Assay Reference Genome Location: Chr.5:36153839 on build GRCh38
• Cytoband: 5p13.2

Target Gene Details

• Entrez Gene ID: 6502
• Gene Name: S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
• Gene Aliases: FBL1, FBXL1, FLB1, p45
• Location: Chr.5:36151989-36192792 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SKP2	NM_001243120.1			NP_001230049.1
	NM_005983.3			NP_005974.2
	NM_032637.3			NP_116026.1
	XM_011514081.2			XP_011512383.1
	XM_011514082.2			XP_011512384.1
	XM_011514083.2			XP_011512385.1
	XM_017009753.1			XP_016865242.1
	AB050979.1			BAB87200.1
	AB050980.1			BAB87201.1
	AB050981.1			BAB87202.1
	AK291255.1
	AK295152.1
	AK296223.1
	AY029177.1			AAK31593.1
	BC001441.2			AAH01441.1
	BC007441.2			AAH07441.1
	U33761.1			AAC50242.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3604707	Chr.5:35513484 - 36501574 on Build GRCh38	Gain	UGT3A1 NADK2 RANBP3L LMBRD2 LOC100506406 UGT3A2 CAPSL MIR580 IL7R SKP2 SPEF2
nsv830262	Chr.5:36074209 - 36293770 on Build GRCh38	Gain	NADK2 RANBP3L LMBRD2 MIR580 SKP2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein polyubiquitination
cell proliferation
anaphase-promoting complex-dependent catabolic process
positive regulation of intracellular estrogen receptor signaling pathway
regulation of apoptotic process
positive regulation of smooth muscle cell proliferation
regulation of cell cycle
cellular response to cell-matrix adhesion
positive regulation of protein polyubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
identical protein binding
ubiquitin protein ligase activity