Hs06134489_cn

• Gene Symbol: PPARD
• Assay Reference Genome Location: Chr.6:35362582 on build GRCh38
• Cytoband: 6p21.31

Target Gene Details

• Entrez Gene ID: 5467
• Gene Name: peroxisome proliferator activated receptor delta
• Gene Aliases: FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB
• Location: Chr.6:35342558-35428191 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPARD	NM_001171818.1			NP_001165289.1
	NM_001171819.1			NP_001165290.1
	NM_001171820.1			NP_001165291.1
	NM_006238.4			NP_006229.1
	NM_177435.2			NP_803184.1
	XM_005249193.1			XP_005249250.1
	XM_006715120.1			XP_006715183.1
	XM_006715123.1			XP_006715186.1
	XM_011514707.1			XP_011513009.1
	XM_011514709.1			XP_011513011.1
	XM_011514710.1			XP_011513012.1
	XM_017010971.1			XP_016866460.1
	XM_017010972.1			XP_016866461.1
	XM_017010973.1			XP_016866462.1
	XM_017010974.1			XP_016866463.1
	AB099507.1			BAC78903.1
	AK122614.1
	AK291661.1
	AK296425.1
	AK304482.1
	AK304878.1
	BC002715.2			AAH02715.1
	BC007578.1			AAH07578.1
	DA192442.1
	DA476590.1
	L07592.1			AAA36469.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830641	Chr.6:35314757 - 35472826 on Build GRCh38	Loss	DEF6 PPARD FANCE RPL10A MIR7111

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
glucose metabolic process
proteoglycan metabolic process
generation of precursor metabolites and energy
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
lipid metabolic process
fatty acid beta-oxidation
vitamin A metabolic process
apoptotic process
heart development
embryo implantation
cholesterol metabolic process
cell proliferation
axon ensheathment
phospholipid biosynthetic process
fatty acid catabolic process
mRNA transcription
response to glucose
positive regulation of phosphatidylinositol 3-kinase signaling
response to activity
regulation of skeletal muscle satellite cell proliferation
negative regulation of smooth muscle cell migration
glucose transport
fatty acid transport
cell differentiation
negative regulation of cell growth
intracellular receptor signaling pathway
cell-substrate adhesion
positive regulation of insulin secretion
negative regulation of collagen biosynthetic process
response to vitamin A
wound healing
negative regulation of apoptotic process
steroid hormone mediated signaling pathway
positive regulation of skeletal muscle tissue regeneration
keratinocyte proliferation
positive regulation of fat cell differentiation
negative regulation of myoblast differentiation
positive regulation of epidermis development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of vasodilation
decidualization
negative regulation of smooth muscle cell proliferation
negative regulation of epithelial cell proliferation
negative regulation of inflammatory response
keratinocyte migration
adipose tissue development
cellular response to lipopolysaccharide
cellular response to hypoxia
apoptotic signaling pathway
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of myoblast proliferation

Function(s)

transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
steroid hormone receptor activity
transcription coactivator activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
transcription factor binding
drug binding
zinc ion binding
lipid binding
sequence-specific DNA binding
protein heterodimerization activity
NF-kappaB binding
linoleic acid binding