Hs06237805_cn

• Gene Symbol: CHRNB3
• Assay Reference Genome Location: Chr.8:42712449 on build GRCh38
• Cytoband: 8p11.21

Target Gene Details

• Entrez Gene ID: 1142
• Gene Name: cholinergic receptor nicotinic beta 3 subunit
• Gene Aliases: -
• Location: Chr.8:42697419-42737407 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CHRNB3	NM_000749.3			NP_000740.1
	BC069681.1			AAH69681.1
	BC069703.1			AAH69703.1
	BC069788.1			AAH69788.1
	U62438.1			AAB40116.1
	X67513.1			CAA47851.1
	Y08417.1			CAA69694.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv7186n100	Chr.8:42688183 - 42763570 on Build GRCh38	Gain	CHRNA6 CHRNB3
nsv1161758	Chr.8:42666258 - 42733252 on Build GRCh38	Duplication	CHRNB3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

transport
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
response to nicotine
protein heterooligomerization
cation transmembrane transport

Function(s)

acetylcholine-activated cation-selective channel activity
drug binding
channel activity
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine binding