Hs06250024_cn

• Gene Symbol: RUNX1T1
• Assay Reference Genome Location: Chr.8:91965823 on build GRCh38
• Cytoband: 8q21.3

Target Gene Details

• Entrez Gene ID: 862
• Gene Name: RUNX1 translocation partner 1
• Gene Aliases: AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
• Location: Chr.8:91954967-92103365 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RUNX1T1	NM_001198625.1			NP_001185554.1
	NM_001198626.1			NP_001185555.1
	NM_001198627.1			NP_001185556.1
	NM_001198628.1			NP_001185557.1
	NM_001198629.1			NP_001185558.1
	NM_001198630.1			NP_001185559.1
	NM_001198631.1			NP_001185560.1
	NM_001198632.1			NP_001185561.1
	NM_001198633.1			NP_001185562.1
	NM_001198634.1			NP_001185563.1
	NM_001198679.1			NP_001185608.1
	NM_004349.3			NP_004340.1
	NM_175634.2			NP_783552.1
	NM_175635.2			NP_783553.1
	NM_175636.2			NP_783554.1
	XM_006716676.3			XP_006716739.1
	XM_011517351.2			XP_011515653.1
	XM_011517352.2			XP_011515654.1
	XM_011517353.2			XP_011515655.1
	XM_017013930.1			XP_016869419.1
	XM_017013931.1			XP_016869420.1
	XM_017013932.1			XP_016869421.1
	XM_017013933.1			XP_016869422.1
	XM_017013934.1			XP_016869423.1
	XM_017013935.1			XP_016869424.1
	XM_017013936.1			XP_016869425.1
	XM_017013937.1			XP_016869426.1
	XM_017013939.1			XP_016869428.1
	XM_017013940.1			XP_016869429.1
	XM_017013941.1			XP_016869430.1
	AF018283.1			AAC26143.1
	AK297616.1
	AK312592.1
	BC005850.1			AAH05850.1
	BC067078.1
	BT009871.1			AAP88873.1
	CR456792.1			CAG33073.1
	D14289.1			BAA03247.1
	D14821.1			BAA03558.1
	D43638.1			BAA07755.1
	KF946509.1
	KF946510.1
	KF946514.1
	KF946518.1
	KF946523.1
	X79990.1			CAA56311.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1022473	Chr.8:91854892 - 94250166 on Build GRCh38	Loss	MIR8084 LINC00535 C8orf87 RUNX1T1 MIR378D2 FAM92A1 TMEM67 LOC105375640 GEM RBM12B-AS1 LOC102724710 TRIQK RBM12B PDP1 FLJ46284 CDH17

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

generation of precursor metabolites and energy
transcription, DNA-templated
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding