Hs06265979_cn

• Gene Symbol: ALKBH8
• Assay Reference Genome Location: Chr.11:107530337 on build GRCh38
• Cytoband: 11q22.3

Target Gene Details

• Entrez Gene ID: 91801
• Gene Name: alkB homolog 8, tRNA methyltransferase
• Gene Aliases: ABH8, TRM9, TRMT9
• Location: Chr.11:107502726-107565740 on Build GRCh38
• Assay Gene Location: Within Intron 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALKBH8	NM_001301010.1			NP_001287939.1
	NM_138775.2			NP_620130.2
	XM_005271728.2			XP_005271785.1
	XM_005271729.3			XP_005271786.1
	XM_017018553.1			XP_016874042.1
	XM_017018554.1			XP_016874043.1
	XM_017018555.1			XP_016874044.1
	XM_017018556.1			XP_016874045.1
	XM_017018557.1			XP_016874046.1
	AB218768.1
	AK293603.1
	AK298800.1
	AK304413.1
	BC015183.1			AAH15183.1
	BX649085.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv556376	Chr.11:107380125 - 107615872 on Build GRCh38	Gain	CWF19L2 ELMOD1 ALKBH8 LOC643923

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

tRNA wobble uridine modification
cellular response to DNA damage stimulus
tRNA methylation
oxidation-reduction process

Function(s)

tRNA binding
nucleotide binding
iron ion binding
protein binding
ferrous iron binding
zinc ion binding
tRNA (uracil) methyltransferase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors