Hs06270023_cn

• Gene Symbol: SERGEF
• Assay Reference Genome Location: Chr.11:17802093 on build GRCh38
• Cytoband: 11p15.1

Target Gene Details

• Entrez Gene ID: 26297
• Gene Name: secretion regulating guanine nucleotide exchange factor
• Gene Aliases: DELGEF, Gnefr
• Location: Chr.11:17788048-18013162 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERGEF	NM_012139.3			NP_036271.1
	NR_104040.1
	NR_104041.1
	AF086056.1
	AJ243950.1			CAB60832.1
	AJ243951.1			CAB60833.1
	AK292286.1
	BC065375.1			AAH65375.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv553567	Chr.11:16890704 - 17946708 on Build GRCh38	Gain	RPS13 MYOD1 KCNC1 SNORD14B KCNJ11 PIK3C2A SERGEF LOC102723330 NUCB2 OTOG ABCC8 USH1C LOC105376575 SNORD14A OR7E14P NCR3LG1 PLEKHA7
nsv526501	Chr.11:17794865 - 17802825 on Build GRCh38	Loss	SERGEF
nsv509390	Chr.11:17726193 - 17855296 on Build GRCh38	Insertion	KCNC1 SERGEF
nsv832078	Chr.11:17758956 - 17931974 on Build GRCh38	Loss	KCNC1 SERGEF

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

signal transduction
positive regulation of GTPase activity
negative regulation of protein secretion

Function(s)

Ran guanyl-nucleotide exchange factor activity
protein binding