Hs06279928_cn

• Gene Symbol: USP47
• Assay Reference Genome Location: Chr.11:11854181 on build GRCh38
• Cytoband: 11p15.3

Target Gene Details

• Entrez Gene ID: 55031
• Gene Name: ubiquitin specific peptidase 47
• Gene Aliases: TRFP
• Location: Chr.11:11841423-11959325 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
USP47	NM_001282659.1			NP_001269588.1
	NM_017944.3			NP_060414.3
	XM_005252997.1			XP_005253054.1
	XM_017017953.1			XP_016873442.1
	AK027362.1			BAB55063.1
	AK092290.1
	AK127264.1
	AK309240.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1054113	Chr.11:11828552 - 11953953 on Build GRCh38	Loss	USP47
nsv512212	Chr.11:11853511 - 11855017 on Build GRCh38	Loss	USP47
esv28059	Chr.11:11854176 - 11855136 on Build GRCh38	Gain+Loss	USP47
nsv483000	Chr.11:10678454 - 12678453 on Build GRCh38	Loss	GALNT18 ZBED5 LOC101928053 SNORD97 MRVI1 TEAD1 LOC105376554 MIR8070 MICALCL CSNK2A3 MIR4299 PARVA EIF4G2 CTR9 MICAL2 USP47 MIR6124 ZBED5-AS1 LOC105376545 DKK3
dgv1655n54	Chr.11:11840666 - 11854702 on Build GRCh38	Loss	USP47
nsv832066	Chr.11:11684853 - 11865904 on Build GRCh38	Gain	MIR8070 USP47
nsv8792	Chr.11:11853289 - 11855203 on Build GRCh38	Gain+Loss	USP47
esv3579369	Chr.11:11853475 - 11861994 on Build GRCh38	Loss	USP47
esv2744114	Chr.11:11853924 - 11855027 on Build GRCh38	Deletion	USP47
nsv553537	Chr.11:11847002 - 11854702 on Build GRCh38	Loss	USP47
esv3625382	Chr.11:11854026 - 11854992 on Build GRCh38	Loss	USP47
dgv52e215	Chr.11:11853863 - 11855056 on Build GRCh38	Deletion	USP47
esv2668480	Chr.11:11854051 - 11855011 on Build GRCh38	Deletion	USP47
nsv832067	Chr.11:11777158 - 11976774 on Build GRCh38	Gain	MIR8070 USP47 DKK3
dgv1656n54	Chr.11:11854200 - 11865070 on Build GRCh38	Loss	USP47
nsv553532	Chr.11:11832323 - 11854702 on Build GRCh38	Loss	USP47

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

base-excision repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
negative regulation of G2/M transition of mitotic cell cycle
positive regulation of cell growth
cellular response to UV
monoubiquitinated protein deubiquitination
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transcription, DNA-templated
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
WD40-repeat domain binding