Hs06299881_cn

• Gene Symbol: RRM1
• Assay Reference Genome Location: Chr.11:4104325 on build GRCh38
• Cytoband: 11p15.4

Target Gene Details

• Entrez Gene ID: 6240
• Gene Name: ribonucleotide reductase catalytic subunit M1
• Gene Aliases: R1, RIR1, RR1
• Location: Chr.11:4094685-4138925 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RRM1	NM_001033.4			NP_001024.1
	NM_001318064.1			NP_001304993.1
	AK222786.1			BAD96506.1
	AK297988.1
	AK299629.1
	AK303394.1
	AK307950.1
	BC006498.2			AAH06498.1
	BP229960.1
	X59543.1			CAA42118.1
	X59617.1			CAA42180.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1053189	Chr.11:4101889 - 4337814 on Build GRCh38	Gain	RRM1 LOC100506082
nsv832053	Chr.11:4075297 - 4309033 on Build GRCh38	Gain	STIM1 RRM1 LOC100506082
esv2759797	Chr.11:4034715 - 4488958 on Build GRCh38	Gain+Loss	OR52K2 OR52K3P STIM1 RRM1 OR52K1 OR52B3P LOC100506082 TRIM21 OR52B4

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase, reductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

mitotic cell cycle
pyrimidine nucleobase metabolic process
DNA replication
male gonad development
deoxyribonucleotide biosynthetic process
response to ionizing radiation
nucleobase-containing small molecule interconversion
cell proliferation in forebrain
protein heterotetramerization
oxidation-reduction process
retina development in camera-type eye

Function(s)

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
protein binding
ATP binding