Hs06308913_cn

• Gene Symbol: RPS3
• Assay Reference Genome Location: Chr.11:75415364 on build GRCh38
• Cytoband: 11q13.4

Target Gene Details

• Entrez Gene ID: 6188
• Gene Name: ribosomal protein S3
• Gene Aliases: S3
• Location: Chr.11:75399491-75422302 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RPS3	NM_001256802.1			NP_001243731.1
	AA976344.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

ribosomal protein

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
DNA repair
transcription, DNA-templated
regulation of transcription, DNA-templated
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
apoptotic process
cellular response to DNA damage stimulus
response to oxidative stress
chromosome segregation
mitotic nuclear division
positive regulation of gene expression
negative regulation of translation
viral transcription
positive regulation of microtubule polymerization
negative regulation of protein ubiquitination
positive regulation of endodeoxyribonuclease activity
DNA damage response, detection of DNA damage
regulation of apoptotic process
positive regulation of JUN kinase activity
negative regulation of DNA repair
positive regulation of DNA repair
spindle assembly
cell division
response to TNF agonist
cellular response to hydrogen peroxide
positive regulation of NIK/NF-kappaB signaling
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA N-glycosylase activity
positive regulation of base-excision repair
positive regulation of apoptotic signaling pathway
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Function(s)

DNA binding
damaged DNA binding
RNA binding
mRNA binding
structural constituent of ribosome
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
microtubule binding
transcription factor binding
tubulin binding
DNA N-glycosylase activity
enzyme binding
kinase binding
protein kinase binding
Hsp70 protein binding
SUMO binding
oxidized purine DNA binding
oxidized pyrimidine DNA binding
ubiquitin-like protein conjugating enzyme binding
poly(A) RNA binding
protein kinase A binding
iron-sulfur cluster binding
Hsp90 protein binding
small ribosomal subunit rRNA binding
supercoiled DNA binding