Hs06412180_cn

• Gene Symbol: SENP3
• Assay Reference Genome Location: Chr.17:7569607 on build GRCh38
• Cytoband: 17p13.1

Target Gene Details

• Entrez Gene ID: 26168
• Gene Name: SUMO1/sentrin/SMT3 specific peptidase 3
• Gene Aliases: SMT3IP1, SSP3, Ulp1
• Location: Chr.17:7561992-7571969 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SENP3	NM_015670.5			NP_056485.2
	AF199459.1			AAL25652.1
	AL050283.1			CAB43384.2
	AL834294.1			CAD38967.1
	AY008763.1			AAG33252.1
	BC048306.1			AAH48306.1
	BC080658.1			AAH80658.1

Target Gene Details

• Entrez Gene ID: 100533955
• Gene Name: SENP3-EIF4A1 readthrough (NMD candidate)
• Gene Aliases: -
• Location: Chr.17:7561992-7579006 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SENP3-EIF4A1	NR_037926.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422288	Chr.17:6789933 - 7646709 on Build GRCh38	Deletion	CLEC10A TEKT1 ELP5 EIF4A1 TMEM256-PLSCR3 GABARAP FXR2 MIR497HG PLSCR3 CHRNB1 CD68 TMEM102 RNASEK-C17orf49 MIR195 ALOX12P2 ALOX12-AS1 ASGR1 TNK1 SLC35G6 SLC2A4 TNFSF12 MIR497 BCL6B FBXO39 DVL2 RNASEK ALOX12 TMEM256 ATP1B2 SNORD10 C17orf74 ASGR2 TNFSF13 TNFSF12-TNFSF13 NLGN2 SLC16A13 C17orf49 SPEM1 EIF5A FGF11 MIR324 PHF23 SNORA48 ACADVL CLDN7 SENP3-EIF4A1 SLC16A11 KCTD11 CTDNEP1 SENP3 SOX15 ZBTB4 TMEM95 SHBG DLG4 YBX2 SNORA67 LOC100996842 POLR2A LOC107983988 ACAP1 GPS2 NEURL4 MPDU1 SAT2
nsv574322	Chr.17:7010333 - 7689462 on Build GRCh38	Loss	CLEC10A ELP5 EIF4A1 WRAP53 TMEM256-PLSCR3 GABARAP FXR2 MIR497HG PLSCR3 CHRNB1 CD68 TMEM102 RNASEK-C17orf49 MIR195 ALOX12-AS1 ASGR1 TNK1 SLC35G6 SLC2A4 TNFSF12 MIR497 BCL6B DVL2 RNASEK ALOX12 TMEM256 ATP1B2 SNORD10 C17orf74 ASGR2 TNFSF13 TNFSF12-TNFSF13 NLGN2 SLC16A13 C17orf49 SPEM1 EIF5A FGF11 MIR324 PHF23 SNORA48 ACADVL CLDN7 SENP3-EIF4A1 SLC16A11 KCTD11 CTDNEP1 SENP3 SOX15 ZBTB4 TMEM95 SHBG DLG4 YBX2 SNORA67 LOC100996842 POLR2A LOC107983988 TP53 ACAP1 GPS2 NEURL4 MPDU1 SAT2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

rRNA processing
protein desumoylation

Function(s)

endopeptidase activity
protein binding
SUMO-specific protease activity