Hs06416082_cn

• Gene Symbol: TOP3A
• Assay Reference Genome Location: Chr.17:18271184 on build GRCh38
• Cytoband: 17p11.2

Target Gene Details

• Entrez Gene ID: 7156
• Gene Name: topoisomerase (DNA) III alpha
• Gene Aliases: TOP3, ZGRF7
• Location: Chr.17:18269958-18315092 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOP3A	XM_011524001.2	14	6029	XP_011522303.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833386	Chr.17:18266947 - 18429412 on Build GRCh38	Gain	MIR6778 EVPLL SMCR8 TOP3A KRT17P5 FLJ35934 KRT17P2 SHMT1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA synthesis involved in DNA repair
strand displacement
DNA replication
DNA topological change
meiotic nuclear division
regulation of signal transduction by p53 class mediator

Function(s)

DNA binding
DNA topoisomerase activity
DNA topoisomerase type I activity
protein binding
zinc ion binding