Hs06434322_cn

• Gene Symbol: SERPINB10
• Assay Reference Genome Location: Chr.18:63924750 on build GRCh38
• Cytoband: 18q22.1

Target Gene Details

• Entrez Gene ID: 5273
• Gene Name: serpin family B member 10
• Gene Aliases: PI-10, PI10
• Location: Chr.18:63907969-63936111 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB10	NM_005024.2			NP_005015.1
	XM_011526027.1			XP_011524329.1
	XM_011526028.1			XP_011524330.1
	XM_017025793.1			XP_016881282.1
	XM_017025794.1			XP_016881283.1
	AK314936.1
	BC096217.3			AAH96217.1
	BC096218.3			AAH96218.1
	BC096219.3			AAH96219.1
	BC096220.3			AAH96220.1
	U35459.1			AAC50282.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	SERPINB12 KDSR LINC00305 SERPINB5 LOC284294 SERPINB4 HMSD SERPINB3 SERPINB13 VPS4B SERPINB10 SERPINB7 SERPINB8 LINC01538 BCL2 SERPINB2 SERPINB11
nsv833673	Chr.18:63897072 - 64097021 on Build GRCh38	Gain	SERPINB10 SERPINB8 LINC00305 SERPINB2 HMSD
esv3642785	Chr.18:63831255 - 63986077 on Build GRCh38	Gain	SERPINB10 SERPINB8 SERPINB2 HMSD
esv21739	Chr.18:63715122 - 64278129 on Build GRCh38	Gain	SERPINB10 SERPINB7 SERPINB8 LINC01538 LINC00305 LOC284294 SERPINB2 SERPINB11 HMSD
nsv1067311	Chr.18:63818011 - 66637685 on Build GRCh38	Loss	SERPINB10 CDH7 SERPINB8 LINC01538 LINC00305 CDH19 LOC284294 SERPINB2 HMSD
nsv525889	Chr.18:63845132 - 63948110 on Build GRCh38	Loss	SERPINB10 SERPINB2
esv3642788	Chr.18:63922332 - 63954216 on Build GRCh38	Gain	SERPINB10 HMSD

More Information

Additional Information:

For this assay, SNP(s) [rs73961817] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
negative regulation of endopeptidase activity
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

serine-type endopeptidase inhibitor activity