Hs06495976_cn

• Gene Symbol: MAPK4
• Assay Reference Genome Location: Chr.18:50569497 on build GRCh38
• Cytoband: 18q21.1

Target Gene Details

• Entrez Gene ID: 5596
• Gene Name: mitogen-activated protein kinase 4
• Gene Aliases: ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK
• Location: Chr.18:50559781-50731826 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAPK4	NM_001292039.1			NP_001278968.1
	NM_001292040.1			NP_001278969.1
	NM_002747.3			NP_002738.2
	XM_011526076.2			XP_011524378.1
	XM_017025839.1			XP_016881328.1
	AK293818.1
	AK295058.1
	BC050299.1
	BX648603.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34028	Chr.18:50358141 - 50744133 on Build GRCh38	Loss	SKA1 MAPK4
nsv9630	Chr.18:50532107 - 50922466 on Build GRCh38	Loss	ME2 MRO MAPK4
nsv833651	Chr.18:50568263 - 50712984 on Build GRCh38	Loss	MAPK4

More Information

Additional Information:

For this assay, SNP(s) [rs67952274] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
protein phosphorylation
cell cycle

Function(s)

protein serine/threonine kinase activity
MAP kinase activity
protein binding
ATP binding
protein kinase binding
protein homodimerization activity
protein heterodimerization activity