Hs06513861_cn

• Gene Symbol: GRIK3
• Assay Reference Genome Location: Chr.1:36815562 on build GRCh38
• Cytoband: 1p34.3

Target Gene Details

• Entrez Gene ID: 2899
• Gene Name: glutamate ionotropic receptor kainate type subunit 3
• Gene Aliases: EAA5, GLR7, GLUR7, GluK3, GluR7a
• Location: Chr.1:36795527-37034243 on Build GRCh38
• Assay Gene Location: Within Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRIK3	NM_000831.3			NP_000822.2
	AJ249210.1			CAC80548.1
	AJ299451.1			CAC44965.1
	U16127.1			AAB60407.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv546001	Chr.1:36692344 - 36841680 on Build GRCh38	Loss	GRIK3
nsv1003721	Chr.1:36716795 - 36849794 on Build GRCh38	Gain	GRIK3

More Information

Additional Information:

For this assay, SNP(s) [rs185653645] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
regulation of membrane potential
negative regulation of synaptic transmission, glutamatergic

Function(s)

adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
G-protein coupled receptor binding
ionotropic glutamate receptor activity
extracellular-glutamate-gated ion channel activity
glutamate receptor activity
ligand-gated ion channel activity
kainate selective glutamate receptor activity