Hs06547102_cn

• Gene Symbol: BCL10
• Assay Reference Genome Location: Chr.1:85271846 on build GRCh38
• Cytoband: 1p22.3

Target Gene Details

• Entrez Gene ID: 8915
• Gene Name: B-cell CLL/lymphoma 10
• Gene Aliases: CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
• Location: Chr.1:85265776-85276904 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BCL10	NM_001320715.1			NP_001307644.1
	NM_003921.4			NP_003912.1
	XM_011542397.2			XP_011540699.1
	XM_011542398.2			XP_011540700.1
	XM_011542399.2			XP_011540701.1
	AF057700.1			AAD15800.1
	AF082283.1			AAC99767.1
	AF100338.1			AAD16428.1
	AF105066.1			AAF06894.1
	AF127386.1			AAD32597.1
	AF134395.1			AAD39147.1
	AJ006288.1			CAA06955.1
	AK291346.1
	BC053617.1			AAH53617.1
	BI831624.1
	BX647306.1
	EF189176.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34165	Chr.1:85076357 - 85380566 on Build GRCh38	Loss	WDR63 C1orf52 SYDE2 DDAH1 BCL10 MIR4423 LOC646626
nsv830459	Chr.1:85123902 - 85320628 on Build GRCh38	Loss	WDR63 C1orf52 SYDE2 DDAH1 BCL10 MIR4423 LOC646626

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

B cell apoptotic process
neural tube closure
stimulatory C-type lectin receptor signaling pathway
toll-like receptor signaling pathway
response to molecule of bacterial origin
adaptive immune response
negative regulation of mature B cell apoptotic process
cellular defense response
I-kappaB kinase/NF-kappaB signaling
cell death
response to fungus
immunoglobulin mediated immune response
positive regulation of protein ubiquitination
response to food
positive regulation of mast cell cytokine production
Fc-epsilon receptor signaling pathway
lymphotoxin A biosynthetic process
interleukin-6 biosynthetic process
positive regulation of phosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
innate immune response
positive regulation of interleukin-8 biosynthetic process
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
protein homooligomerization
protein heterooligomerization
T cell apoptotic process
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
transcription coactivator activity
protein binding
protein C-terminus binding
transcription factor binding
kinase activator activity
enzyme binding
kinase binding
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
ubiquitin binding
protein kinase B binding
protein self-association
NF-kappaB binding