Hs06573815_cn

• Gene Symbol: MAD2L2
• Assay Reference Genome Location: Chr.1:11681380 on build GRCh38
• Cytoband: 1p36.22

Target Gene Details

• Entrez Gene ID: 10459
• Gene Name: MAD2 mitotic arrest deficient-like 2 (yeast)
• Gene Aliases: MAD2B, POLZ2, REV7
• Location: Chr.1:11674480-11691788 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MAD2L2	NM_001127325.1			NP_001120797.1
	XM_011540507.1			XP_011538809.1
	AK094316.1	3	577
	BI517654.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832758	Chr.1:11637026 - 11777087 on Build GRCh38	Loss	FBXO44 LOC102724659 AGTRAP C1orf167 DRAXIN MAD2L2 FBXO6 FBXO2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth
double-strand break repair
transcription, DNA-templated
actin filament organization
mitotic nuclear division
mitotic spindle assembly checkpoint
negative regulation of epithelial to mesenchymal transition
negative regulation of transcription by competitive promoter binding
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein catabolic process
error-prone translesion synthesis
DNA damage response, signal transduction resulting in transcription
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of transcription, DNA-templated
cell division
negative regulation of canonical Wnt signaling pathway
negative regulation of ubiquitin protein ligase activity
negative regulation of cell-cell adhesion mediated by cadherin
negative regulation of transcription regulatory region DNA binding

Function(s)

RNA polymerase II activating transcription factor binding
protein binding
JUN kinase binding