Hs06575259_cn

• Gene Symbol: PAPPA2
• Assay Reference Genome Location: Chr.1:176464688 on build GRCh38
• Cytoband: 1q25.2

Target Gene Details

• Entrez Gene ID: 60676
• Gene Name: pappalysin 2
• Gene Aliases: PAPP-A2, PAPP-E, PAPPE, PLAC3
• Location: Chr.1:176463159-176845601 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PAPPA2	NM_020318.2			NP_064714.2
	NM_021936.2			NP_068755.2
	XM_011509857.1			XP_011508159.1
	XM_017002023.1			XP_016857512.1
	XM_017002024.1			XP_016857513.1
	AF342989.1			AAL17779.1
	AF342990.1			AAL17780.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831970	Chr.1:176417026 - 176600071 on Build GRCh38	Gain	PAPPA2
nsv1004658	Chr.1:176443038 - 176491284 on Build GRCh38	Gain	PAPPA2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

regulation of cell growth
proteolysis
cellular protein metabolic process
bone morphogenesis

Function(s)

metalloendopeptidase activity
metallopeptidase activity
zinc ion binding