Hs06700891_cn

• Gene Symbol: PIK3CB
• Assay Reference Genome Location: Chr.3:138653939 on build GRCh38
• Cytoband: 3q22.3

Target Gene Details

• Entrez Gene ID: 5291
• Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
• Gene Aliases: P110BETA, PI3K, PI3KBETA, PIK3C1
• Location: Chr.3:138652698-138834938 on Build GRCh38
• Assay Gene Location: Within Exon 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIK3CB	NM_001256045.1	13	3545	NP_001242974.1
	NM_006219.2	22	4679	NP_006210.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv591854	Chr.3:138629239 - 139045387 on Build GRCh38	Gain	PRR23B LINC01391 FAIM FOXL2NB PIK3CB PRR23C PRR23A FOXL2
nsv428422	Chr.3:137344347 - 138686784 on Build GRCh38	Gain+Loss	A4GNT ARMC8 PIK3CB DZIP1L MRAS CLDN18 CEP70 DBR1 ESYT3 NME9 FAIM SOX14 LINC01210
dgv4908n100	Chr.3:138494324 - 139018846 on Build GRCh38	Gain	LINC01391 FAIM FOXL2NB PIK3CB PRR23A CEP70 FOXL2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

activation of MAPK activity
endothelial cell proliferation
regulation of cell-matrix adhesion
phosphatidylinositol biosynthetic process
cellular calcium ion homeostasis
autophagy
chemotaxis
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of autophagy
positive regulation of gene expression
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
cell migration
platelet activation
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
embryonic cleavage
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
angiogenesis involved in wound healing
platelet aggregation
regulation of clathrin-mediated endocytosis

Function(s)

protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase activity
1-phosphatidylinositol-4-phosphate 3-kinase activity
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity