Hs06784311_cn

• Gene Symbol: PRDM1
• Assay Reference Genome Location: Chr.6:106091253 on build GRCh38
• Cytoband: 6q21

Target Gene Details

• Entrez Gene ID: 639
• Gene Name: PR domain 1
• Gene Aliases: BLIMP1, PRDI-BF1
• Location: Chr.6:106046729-106109939 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRDM1	NM_001198.3			NP_001189.2
	XM_006715550.3			XP_006715613.1
	XM_011536062.2			XP_011534364.1
	XM_011536063.2			XP_011534365.1
	XM_017011187.1			XP_016866676.1
	AF084199.1			AAC33300.1
	AK289556.1
	AL832963.1			CAH56276.1
	AY198414.1			AAO45623.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1025231	Chr.6:106003137 - 106186514 on Build GRCh38	Gain	ATG5 PRDM1
dgv6134n100	Chr.6:106081902 - 106464172 on Build GRCh38	Gain	LOC105377924 ATG5 PRDM1 AIM1
nsv830755	Chr.6:106013830 - 106176327 on Build GRCh38	Loss	PRDM1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
morphogenesis of a branching structure
maternal placenta development
heart valve development
ventricular septum development
transcription, DNA-templated
germ cell development
post-embryonic development
positive regulation of gene expression
negative regulation of B cell proliferation
negative regulation of lipopolysaccharide-mediated signaling pathway
methylation
regulation of natural killer cell differentiation
regulation of extrathymic T cell differentiation
aorta development
eye photoreceptor cell development
cell fate commitment
positive regulation of B cell differentiation
artery morphogenesis
regulation of NK T cell differentiation
intestinal epithelial cell development
trophoblast giant cell differentiation
coronary vasculature development
sebum secreting cell proliferation

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
methyltransferase activity
histone deacetylase binding
metal ion binding
promoter-specific chromatin binding