Hs06829753_cn

• Gene Symbol: SEC61B
• Assay Reference Genome Location: Chr.9:99226792 on build GRCh38
• Cytoband: 9q22.33

Target Gene Details

• Entrez Gene ID: 10952
• Gene Name: Sec61 translocon beta subunit
• Gene Aliases: -
• Location: Chr.9:99222288-99230619 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SEC61B	NM_006808.2			NP_006799.1
	AJ293399.1
	AK223384.1			BAD97104.1
	BC001734.1			AAH01734.1
	CR456883.1			CAG33164.1
	CR542159.1			CAG46956.1
	L25085.1			AAA19706.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3621214	Chr.9:98651384 - 99637088 on Build GRCh38	Gain	SEC61B COL15A1 ANKS6 NAMA LOC101928438 GABBR2 GALNT12 ALG2 TGFBR1
nsv831666	Chr.9:99112703 - 99256408 on Build GRCh38	Gain	SEC61B ALG2 TGFBR1

More Information

Additional Information:

For this assay, SNP(s) [rs75668500] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

protein import into nucleus, translocation
ER-associated ubiquitin-dependent protein catabolic process
retrograde protein transport, ER to cytosol
IRE1-mediated unfolded protein response

Function(s)

protein binding
poly(A) RNA binding
epidermal growth factor binding